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تداخل‌های دارویی

Hydrocortisone + Smallpox vaccine live

شدت: منع مصرف

Hydrocortisone and Smallpox vaccine live: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Live vaccinia vaccine can cause progressive vaccinia and other severe complications in immunocompromised patients. Corticosteroid immunosuppression increases this risk and may reduce vaccine take.

معنای این تداخل به زبان ساده

Hydrocortisone and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

سطح شواهد: Moderate

چرا رخ می‌دهد

Corticosteroid-induced immunosuppression allows uncontrolled replication of live vaccinia virus.

اقدام لازم

Avoid in patients on immunosuppressive corticosteroids unless the benefit clearly outweighs risk, such as in post-exposure outbreak settings, and seek specialist advice. Use a non-replicating vaccine if available.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Hydrocortisone و Smallpox vaccine live، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Hydrocortisone with Smallpox vaccine live?

MediHelp rates the interaction as contraindicated. Hydrocortisone and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live vaccinia vaccine can cause progressive vaccinia and other severe complications in immunocompromised patients. Corticosteroid immunosuppression increases this risk and may reduce vaccine take.

How serious is the interaction between Hydrocortisone and Smallpox vaccine live?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid in patients on immunosuppressive corticosteroids unless the benefit clearly outweighs risk, such as in post-exposure outbreak settings, and seek specialist advice. Use a non-replicating vaccine if available.

What other medicines interact with Hydrocortisone?

MediHelp also lists interactions of Hydrocortisone with, for example, Mifepristone, Poliovirus vaccine live oral trivalent, Adenovirus types 4 and 7 live. The full list is on the Hydrocortisone page.

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