تداخل‌های دارویی
Adefovir + Streptomycin
شدت: شدید
Adefovir and Streptomycin: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Adefovir can cause dose-related proximal tubular nephrotoxicity, and streptomycin is also nephrotoxic. Concurrent use increases the risk of kidney injury and may raise aminoglycoside exposure and ototoxicity.
معنای این تداخل به زبان ساده
Adefovir and Streptomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Adefovir belongs to Anti Virals; Streptomycin belongs to Anti Bacterial.
چرا رخ می‌دهد
Additive nephrotoxicity affecting the proximal tubule, with reduced clearance of renally eliminated drugs.
اقدام لازم
Avoid concurrent use when possible. If necessary, monitor serum creatinine and phosphate regularly, adjust adefovir dosing interval to renal function, and monitor streptomycin levels and hearing.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Adefovir و Streptomycin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Streptomycin
تداخلات دیگر Adefovir
پرسش‌های متداول
Can I take Adefovir with Streptomycin?
MediHelp rates the interaction as major. Adefovir and Streptomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Adefovir can cause dose-related proximal tubular nephrotoxicity, and streptomycin is also nephrotoxic. Concurrent use increases the risk of kidney injury and may raise aminoglycoside exposure and ototoxicity.
How serious is the interaction between Adefovir and Streptomycin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use when possible. If necessary, monitor serum creatinine and phosphate regularly, adjust adefovir dosing interval to renal function, and monitor streptomycin levels and hearing.
What other medicines interact with Streptomycin?
MediHelp also lists interactions of Streptomycin with, for example, Abobotulinumtoxina, Amikacin, Amphotericin b deoxycholate. The full list is on the Streptomycin page.
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