تداخل‌های دارویی
Allopurinol + Ampicillin
شدت: متوسط
Allopurinol and Ampicillin: moderate interaction.
آخرین به‌روزرسانی
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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Patients taking allopurinol together with ampicillin have a higher reported frequency of skin rash than those taking either drug alone. The rash is generally mild and may be hard to tell apart from allopurinol hypersensitivity, which can occasionally be serious.
معنای این تداخل به زبان ساده
Allopurinol and Ampicillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Allopurinol belongs to Genitourinary; Ampicillin belongs to Anti Bacterial.
چرا رخ می‌دهد
The mechanism is not established; an additive or synergistic hypersensitivity-type reaction has been proposed.
اقدام لازم
Counsel the patient to report any rash promptly and evaluate it carefully for allopurinol hypersensitivity. If a rash appears, stop allopurinol and consider an alternative antibiotic.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Allopurinol و Ampicillin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Allopurinol
تداخلات دیگر Ampicillin
پرسش‌های متداول
Can I take Allopurinol with Ampicillin?
MediHelp rates the interaction as moderate. Allopurinol and Ampicillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Patients taking allopurinol together with ampicillin have a higher reported frequency of skin rash than those taking either drug alone. The rash is generally mild and may be hard to tell apart from allopurinol hypersensitivity, which can occasionally be serious.
How serious is the interaction between Allopurinol and Ampicillin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel the patient to report any rash promptly and evaluate it carefully for allopurinol hypersensitivity. If a rash appears, stop allopurinol and consider an alternative antibiotic.
What other medicines interact with Allopurinol?
MediHelp also lists interactions of Allopurinol with, for example, Azathioprine, Didanosine, Mercaptopurine. The full list is on the Allopurinol page.
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