تداخل‌های دارویی
Amikacin + Cisatracurium
شدت: شدید
Amikacin and Cisatracurium: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Aminoglycosides have intrinsic neuromuscular blocking activity and can potentiate nondepolarising blockers such as cisatracurium. This can prolong paralysis and delay recovery of spontaneous breathing, with a risk of apnoea.
معنای این تداخل به زبان ساده
Amikacin and Cisatracurium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amikacin belongs to Anti Bacterial; Cisatracurium belongs to Musculoskeletal.
چرا رخ می‌دهد
Aminoglycoside reduction of presynaptic acetylcholine release and postsynaptic sensitivity, additive to nondepolarising blockade.
اقدام لازم
Monitor neuromuscular function with train-of-four and reduce cisatracurium doses as needed. Ensure ventilatory support is available and recovery is complete before extubation.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Amikacin و Cisatracurium، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Cisatracurium
تداخلات دیگر Amikacin
پرسش‌های متداول
Can I take Amikacin with Cisatracurium?
MediHelp rates the interaction as major. Amikacin and Cisatracurium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Aminoglycosides have intrinsic neuromuscular blocking activity and can potentiate nondepolarising blockers such as cisatracurium. This can prolong paralysis and delay recovery of spontaneous breathing, with a risk of apnoea.
How serious is the interaction between Amikacin and Cisatracurium?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor neuromuscular function with train-of-four and reduce cisatracurium doses as needed. Ensure ventilatory support is available and recovery is complete before extubation.
What other medicines interact with Cisatracurium?
MediHelp also lists interactions of Cisatracurium with, for example, Bacitracin-neomycin-polymyxin, Benzhydrocodone / acetaminophen, Capreomycin. The full list is on the Cisatracurium page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
