تداخل‌های دارویی
Amikacin + Rocuronium
شدت: شدید
Amikacin and Rocuronium: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Amikacin can intensify and prolong neuromuscular blockade from rocuronium. This may lead to delayed recovery, respiratory depression or apnea, especially in renal impairment.
معنای این تداخل به زبان ساده
Amikacin and Rocuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amikacin belongs to Anti Bacterial; Rocuronium belongs to Musculoskeletal.
چرا رخ می‌دهد
Aminoglycosides inhibit presynaptic acetylcholine release and reduce postsynaptic sensitivity, adding to competitive nicotinic blockade.
اقدام لازم
Monitor with train-of-four and reduce rocuronium dosing as needed. Keep ventilatory support available until full recovery is confirmed.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Amikacin و Rocuronium، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Rocuronium
تداخلات دیگر Amikacin
پرسش‌های متداول
Can I take Amikacin with Rocuronium?
MediHelp rates the interaction as major. Amikacin and Rocuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Amikacin can intensify and prolong neuromuscular blockade from rocuronium. This may lead to delayed recovery, respiratory depression or apnea, especially in renal impairment.
How serious is the interaction between Amikacin and Rocuronium?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor with train-of-four and reduce rocuronium dosing as needed. Keep ventilatory support available until full recovery is confirmed.
What other medicines interact with Rocuronium?
MediHelp also lists interactions of Rocuronium with, for example, Bacitracin-neomycin-polymyxin, Capreomycin, Clindamycin. The full list is on the Rocuronium page.
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