تداخل‌های دارویی
Capreomycin + Rocuronium
شدت: شدید
Capreomycin and Rocuronium: major interaction.
آخرین به‌روزرسانی
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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Capreomycin has neuromuscular blocking activity and can intensify and prolong non-depolarizing blockade from rocuronium. This can result in prolonged paralysis and respiratory insufficiency, especially with renal impairment.
معنای این تداخل به زبان ساده
Capreomycin and Rocuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
چرا رخ می‌دهد
Additive neuromuscular blockade through intrinsic curare-like effects of capreomycin at the neuromuscular junction.
اقدام لازم
Avoid combining when alternatives exist; otherwise reduce rocuronium dose and monitor with train-of-four until full recovery. Have ventilatory support ready and consider renal function.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Capreomycin و Rocuronium، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Rocuronium
پرسش‌های متداول
Can I take Capreomycin with Rocuronium?
MediHelp rates the interaction as major. Capreomycin and Rocuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Capreomycin has neuromuscular blocking activity and can intensify and prolong non-depolarizing blockade from rocuronium. This can result in prolonged paralysis and respiratory insufficiency, especially with renal impairment.
How serious is the interaction between Capreomycin and Rocuronium?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining when alternatives exist; otherwise reduce rocuronium dose and monitor with train-of-four until full recovery. Have ventilatory support ready and consider renal function.
What other medicines interact with Rocuronium?
MediHelp also lists interactions of Rocuronium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Clindamycin. The full list is on the Rocuronium page.
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