تداخل‌های دارویی
Amitriptyline + Macimorelin
شدت: شدید
Amitriptyline and Macimorelin: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Macimorelin modestly prolongs the QT interval and amitriptyline has additional QT-prolonging potential, which could increase the risk of torsades de pointes during the diagnostic test. Macimorelin is given as a single test dose, so exposure is short.
معنای این تداخل به زبان ساده
Amitriptyline and Macimorelin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amitriptyline belongs to Central Nervous System; Macimorelin belongs to Endocrine.
چرا رخ می‌دهد
Additive QT interval prolongation.
اقدام لازم
Avoid the combination. Where feasible, withhold amitriptyline for an adequate washout before the test, or use another growth hormone stimulation test.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Amitriptyline و Macimorelin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Amitriptyline
- Amitriptyline + Isocarboxazid منع مصرف
- Amitriptyline + Methylene blue منع مصرف
- Amitriptyline + Phenelzine منع مصرف
- Amitriptyline + Pimozide منع مصرف
- Amitriptyline + Procarbazine منع مصرف
- Amitriptyline + Safinamide منع مصرف
تداخلات دیگر Macimorelin
پرسش‌های متداول
Can I take Amitriptyline with Macimorelin?
MediHelp rates the interaction as major. Amitriptyline and Macimorelin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Macimorelin modestly prolongs the QT interval and amitriptyline has additional QT-prolonging potential, which could increase the risk of torsades de pointes during the diagnostic test. Macimorelin is given as a single test dose, so exposure is short.
How serious is the interaction between Amitriptyline and Macimorelin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination. Where feasible, withhold amitriptyline for an adequate washout before the test, or use another growth hormone stimulation test.
What other medicines interact with Amitriptyline?
MediHelp also lists interactions of Amitriptyline with, for example, Isocarboxazid, Methylene blue, Phenelzine. The full list is on the Amitriptyline page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
