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تداخل‌های دارویی

Apixaban + Eptifibatide

شدت: شدید

Apixaban and Eptifibatide: major interaction.

آخرین به‌روزرسانی

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خلاصه

Eptifibatide blocks platelet glycoprotein IIb/IIIa receptors and, with apixaban, substantially increases the risk of serious bleeding. It is used in acute coronary settings where anticoagulation overlap may occur.

معنای این تداخل به زبان ساده

Apixaban and Eptifibatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Apixaban belongs to Cardiovascular; Eptifibatide belongs to Cardiovascular.

سطح شواهد: Moderate

چرا رخ می‌دهد

Additive hemostatic impairment from platelet aggregation blockade and factor Xa inhibition.

اقدام لازم

Avoid unless clearly necessary; if combined, monitor closely for bleeding and check hemoglobin and renal function. Consider holding apixaban during the infusion per the treating cardiology team.

از داروساز چه بپرسید

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Apixaban و Eptifibatide، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Apixaban with Eptifibatide?

MediHelp rates the interaction as major. Apixaban and Eptifibatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Eptifibatide blocks platelet glycoprotein IIb/IIIa receptors and, with apixaban, substantially increases the risk of serious bleeding. It is used in acute coronary settings where anticoagulation overlap may occur.

How serious is the interaction between Apixaban and Eptifibatide?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid unless clearly necessary; if combined, monitor closely for bleeding and check hemoglobin and renal function. Consider holding apixaban during the infusion per the treating cardiology team.

What other medicines interact with Apixaban?

MediHelp also lists interactions of Apixaban with, for example, Dabigatran, Defibrotide, Edoxaban. The full list is on the Apixaban page.

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