تداخل‌های دارویی
Arsenic trioxide + Octreotide
شدت: شدید
Arsenic trioxide and Octreotide: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Arsenic trioxide carries a boxed warning for QT prolongation and torsades de pointes, and octreotide can add to this through bradycardia and QT effects. The combination raises the risk of serious ventricular arrhythmia.
معنای این تداخل به زبان ساده
Arsenic trioxide and Octreotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Arsenic trioxide belongs to Oncology; Octreotide belongs to Endocrine.
چرا رخ می‌دهد
Additive QT prolongation, with octreotide-related bradycardia increasing torsades risk.
اقدام لازم
Avoid the combination where possible. If it is necessary, obtain a baseline ECG, keep potassium and magnesium within normal range, and monitor ECG throughout therapy.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Arsenic trioxide و Octreotide، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Octreotide
تداخلات دیگر Arsenic trioxide
- Amiodarone + Arsenic trioxide منع مصرف
- Amisulpride + Arsenic trioxide منع مصرف
- Arsenic trioxide + Clomipramine منع مصرف
- Arsenic trioxide + Dronedarone منع مصرف
- Arsenic trioxide + Fluphenazine منع مصرف
- Arsenic trioxide + Gemifloxacin منع مصرف
پرسش‌های متداول
Can I take Arsenic trioxide with Octreotide?
MediHelp rates the interaction as major. Arsenic trioxide and Octreotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Arsenic trioxide carries a boxed warning for QT prolongation and torsades de pointes, and octreotide can add to this through bradycardia and QT effects. The combination raises the risk of serious ventricular arrhythmia.
How serious is the interaction between Arsenic trioxide and Octreotide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible. If it is necessary, obtain a baseline ECG, keep potassium and magnesium within normal range, and monitor ECG throughout therapy.
What other medicines interact with Octreotide?
MediHelp also lists interactions of Octreotide with, for example, Adagrasib, Amisulpride, Artemether / lumefantrine. The full list is on the Octreotide page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
