تداخل‌های دارویی
Disopyramide + Octreotide
شدت: شدید
Disopyramide and Octreotide: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Octreotide can cause bradycardia and conduction abnormalities and has been associated with QT prolongation, while disopyramide prolongs QT and can cause torsades de pointes. Combined use may raise arrhythmia risk, especially with electrolyte disturbances.
معنای این تداخل به زبان ساده
Disopyramide and Octreotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Disopyramide belongs to Cardiovascular; Octreotide belongs to Endocrine.
چرا رخ می‌دهد
Additive effects on cardiac repolarization and conduction, plus octreotide-related bradycardia.
اقدام لازم
Avoid if possible; otherwise obtain baseline and follow-up ECGs and correct potassium and magnesium.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Disopyramide و Octreotide، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Octreotide
تداخلات دیگر Disopyramide
- Amisulpride + Disopyramide منع مصرف
- Desipramine + Disopyramide منع مصرف
- Disopyramide + Dronedarone منع مصرف
- Disopyramide + Itraconazole منع مصرف
- Disopyramide + Ketoconazole منع مصرف
- Disopyramide + Maprotiline منع مصرف
پرسش‌های متداول
Can I take Disopyramide with Octreotide?
MediHelp rates the interaction as major. Disopyramide and Octreotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Octreotide can cause bradycardia and conduction abnormalities and has been associated with QT prolongation, while disopyramide prolongs QT and can cause torsades de pointes. Combined use may raise arrhythmia risk, especially with electrolyte disturbances.
How serious is the interaction between Disopyramide and Octreotide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if possible; otherwise obtain baseline and follow-up ECGs and correct potassium and magnesium.
What other medicines interact with Octreotide?
MediHelp also lists interactions of Octreotide with, for example, Adagrasib, Amisulpride, Arsenic trioxide. The full list is on the Octreotide page.
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