تداخل‌های دارویی
Ascorbic acid + Deferoxamine
شدت: شدید
Ascorbic acid and Deferoxamine: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Vitamin C mobilizes storage iron and makes more of it available for chelation by deferoxamine, increasing iron excretion. In iron-overloaded patients, especially with cardiac disease, high-dose vitamin C has been linked to cardiac decompensation and arrhythmia.
معنای این تداخل به زبان ساده
Ascorbic acid and Deferoxamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
چرا رخ می‌دهد
Ascorbic acid increases the pool of chelatable iron, and the redox-active iron released may cause cardiac toxicity.
اقدام لازم
Avoid ascorbic acid in patients with cardiac dysfunction on deferoxamine. If used in others, start only after deferoxamine is established, keep doses low and give it with the infusion, with cardiac monitoring.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Ascorbic acid و Deferoxamine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Deferoxamine
پرسش‌های متداول
Can I take Ascorbic acid with Deferoxamine?
MediHelp rates the interaction as major. Ascorbic acid and Deferoxamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Vitamin C mobilizes storage iron and makes more of it available for chelation by deferoxamine, increasing iron excretion. In iron-overloaded patients, especially with cardiac disease, high-dose vitamin C has been linked to cardiac decompensation and arrhythmia.
How serious is the interaction between Ascorbic acid and Deferoxamine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid ascorbic acid in patients with cardiac dysfunction on deferoxamine. If used in others, start only after deferoxamine is established, keep doses low and give it with the infusion, with cardiac monitoring.
What other medicines interact with Deferoxamine?
MediHelp also lists interactions of Deferoxamine with, for example, Betibeglogene autotemcel, Exagamglogene autotemcel, Lovotibeglogene autotemcel. The full list is on the Deferoxamine page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
