تداخل‌های دارویی
Deferoxamine + Vitamin c
شدت: شدید
Deferoxamine and Vitamin c: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Vitamin C increases the amount of iron available for chelation by deferoxamine and can raise urinary iron excretion. In iron-overloaded patients, especially those with cardiac involvement, high-dose vitamin C has been linked to cardiac dysfunction, which can be serious.
معنای این تداخل به زبان ساده
Deferoxamine and Vitamin c can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Deferoxamine belongs to Miscellaneous; Vitamin c belongs to Gastrointestinal Tract.
چرا رخ می‌دهد
Ascorbic acid mobilizes tissue iron into a labile pool, which may increase iron-mediated myocardial toxicity while enhancing deferoxamine chelation.
اقدام لازم
Avoid vitamin C in patients with cardiac dysfunction receiving deferoxamine. If it is used, start it only after a month of regular chelation, keep doses low, and monitor cardiac function.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Deferoxamine و Vitamin c، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۷ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Vitamin c
تداخلات دیگر Deferoxamine
پرسش‌های متداول
Can I take Deferoxamine with Vitamin c?
MediHelp rates the interaction as major. Deferoxamine and Vitamin c can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Vitamin C increases the amount of iron available for chelation by deferoxamine and can raise urinary iron excretion. In iron-overloaded patients, especially those with cardiac involvement, high-dose vitamin C has been linked to cardiac dysfunction, which can be serious.
How serious is the interaction between Deferoxamine and Vitamin c?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid vitamin C in patients with cardiac dysfunction receiving deferoxamine. If it is used, start it only after a month of regular chelation, keep doses low, and monitor cardiac function.
What other medicines interact with Vitamin c?
MediHelp also lists interactions of Vitamin c with, for example, Aluminum hydroxide, Dextroamphetamine transdermal, Aspirin / citric acid / sodium bicarbonate. The full list is on the Vitamin c page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
