تداخل‌های دارویی
Bacitracin-neomycin-polymyxin + Vecuronium
شدت: شدید
Bacitracin-neomycin-polymyxin and Vecuronium: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Polymyxin B and neomycin can potentiate vecuronium's neuromuscular blockade. This may prolong paralysis and delay recovery of spontaneous breathing. The risk is mainly with systemic or irrigation use, not small topical areas.
معنای این تداخل به زبان ساده
Bacitracin-neomycin-polymyxin and Vecuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bacitracin-neomycin-polymyxin belongs to Anti Bacterial; Vecuronium belongs to Musculoskeletal.
چرا رخ می‌دهد
Additive pharmacodynamic neuromuscular blockade through reduced presynaptic acetylcholine release and postsynaptic receptor effects.
اقدام لازم
Avoid systemic, irrigation or large-area combination antibiotic exposure during neuromuscular blockade where possible. If used, monitor neuromuscular function with train-of-four and ensure ventilatory support is available.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Bacitracin-neomycin-polymyxin و Vecuronium، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Bacitracin-neomycin-polymyxin
- Allogeneic cultured keratinocytes / fibroblasts in bovine collagen + Bacitracin-neomycin-polymyxin شدید
- Atracurium + Bacitracin-neomycin-polymyxin شدید
- Bacitracin-neomycin-polymyxin + Capreomycin شدید
- Bacitracin-neomycin-polymyxin + Cidofovir شدید
- Bacitracin-neomycin-polymyxin + Cisatracurium شدید
- Bacitracin-neomycin-polymyxin + Pancuronium شدید
تداخلات دیگر Vecuronium
پرسش‌های متداول
Can I take Bacitracin-neomycin-polymyxin with Vecuronium?
MediHelp rates the interaction as major. Bacitracin-neomycin-polymyxin and Vecuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Polymyxin B and neomycin can potentiate vecuronium's neuromuscular blockade. This may prolong paralysis and delay recovery of spontaneous breathing. The risk is mainly with systemic or irrigation use, not small topical areas.
How serious is the interaction between Bacitracin-neomycin-polymyxin and Vecuronium?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid systemic, irrigation or large-area combination antibiotic exposure during neuromuscular blockade where possible. If used, monitor neuromuscular function with train-of-four and ensure ventilatory support is available.
What other medicines interact with Bacitracin-neomycin-polymyxin?
MediHelp also lists interactions of Bacitracin-neomycin-polymyxin with, for example, Allogeneic cultured keratinocytes / fibroblasts in bovine collagen, Atracurium, Capreomycin. The full list is on the Bacitracin-neomycin-polymyxin page.
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