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تداخل‌های دارویی

Baricitinib + Etrasimod

شدت: شدید

Baricitinib and Etrasimod: major interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Both drugs suppress immune function, so using them together may add to the risk of serious infection. Etrasimod lowers circulating lymphocytes and its effect persists for weeks after the last dose. The combination has not been studied.

معنای این تداخل به زبان ساده

Baricitinib and Etrasimod can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Baricitinib belongs to Musculoskeletal; Etrasimod belongs to Gastrointestinal Tract.

سطح شواهد: Low

چرا رخ می‌دهد

Additive immunosuppression through JAK inhibition and S1P receptor modulation with lymphocyte sequestration.

اقدام لازم

Avoid concurrent use and for several weeks after stopping etrasimod. If unavoidable, monitor closely for infection and check lymphocyte counts.

از داروساز چه بپرسید

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Baricitinib و Etrasimod، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Baricitinib with Etrasimod?

MediHelp rates the interaction as major. Baricitinib and Etrasimod can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs suppress immune function, so using them together may add to the risk of serious infection. Etrasimod lowers circulating lymphocytes and its effect persists for weeks after the last dose. The combination has not been studied.

How serious is the interaction between Baricitinib and Etrasimod?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and for several weeks after stopping etrasimod. If unavoidable, monitor closely for infection and check lymphocyte counts.

What other medicines interact with Baricitinib?

MediHelp also lists interactions of Baricitinib with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Tofacitinib. The full list is on the Baricitinib page.

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