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تداخل‌های دارویی

Bcg vaccine live + Fingolimod

شدت: منع مصرف

Bcg vaccine live and Fingolimod: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Fingolimod reduces lymphocyte trafficking, so live BCG may replicate uncontrollably and cause disseminated BCG infection. The vaccine response may also be reduced.

معنای این تداخل به زبان ساده

Bcg vaccine live and Fingolimod are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

سطح شواهد: Moderate

چرا رخ می‌دهد

Fingolimod-induced lymphocyte sequestration impairs immune control of live attenuated bacteria and reduces vaccine response.

اقدام لازم

Avoid live vaccines during fingolimod therapy and for about two months after stopping it. Give required live vaccines at least four weeks before starting fingolimod.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Bcg vaccine live و Fingolimod، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Bcg vaccine live with Fingolimod?

MediHelp rates the interaction as contraindicated. Bcg vaccine live and Fingolimod are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Fingolimod reduces lymphocyte trafficking, so live BCG may replicate uncontrollably and cause disseminated BCG infection. The vaccine response may also be reduced.

How serious is the interaction between Bcg vaccine live and Fingolimod?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during fingolimod therapy and for about two months after stopping it. Give required live vaccines at least four weeks before starting fingolimod.

What other medicines interact with Fingolimod?

MediHelp also lists interactions of Fingolimod with, for example, Adenovirus types 4 and 7 live, Pimozide, Ponesimod. The full list is on the Fingolimod page.

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