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تداخل‌های دارویی

Bcg vaccine live + Lomustine

شدت: منع مصرف

Bcg vaccine live and Lomustine: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Lomustine suppresses bone marrow and immune function, so live BCG may cause disseminated BCG infection. Vaccine efficacy is also reduced.

معنای این تداخل به زبان ساده

Bcg vaccine live and Lomustine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

سطح شواهد: High

چرا رخ می‌دهد

Cytotoxic immunosuppression impairs control of live vaccine bacteria and reduces the immune response.

اقدام لازم

Avoid BCG vaccination during lomustine therapy and until immune recovery, generally at least 3 months after stopping. Seek specialist advice if exposure risk is high.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Bcg vaccine live و Lomustine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Bcg vaccine live with Lomustine?

MediHelp rates the interaction as contraindicated. Bcg vaccine live and Lomustine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Lomustine suppresses bone marrow and immune function, so live BCG may cause disseminated BCG infection. Vaccine efficacy is also reduced.

How serious is the interaction between Bcg vaccine live and Lomustine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid BCG vaccination during lomustine therapy and until immune recovery, generally at least 3 months after stopping. Seek specialist advice if exposure risk is high.

What other medicines interact with Lomustine?

MediHelp also lists interactions of Lomustine with, for example, Adenovirus types 4 and 7 live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Lomustine page.

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