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تداخل‌های دارویی

Belimumab + Human papillomavirus vaccine

شدت: متوسط

Belimumab and Human papillomavirus vaccine: moderate interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Belimumab suppresses B-cell survival and may blunt the antibody response to HPV vaccination. Protection may therefore be lower than expected, although the vaccine is non-live and not unsafe.

معنای این تداخل به زبان ساده

Belimumab and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Belimumab belongs to Miscellaneous; Human papillomavirus vaccine belongs to Miscellaneous.

سطح شواهد: Low

چرا رخ می‌دهد

Pharmacodynamic antagonism: belimumab inhibits BLyS and reduces B-cell mediated humoral immune responses.

اقدام لازم

Where possible, complete HPV vaccination before starting belimumab. If given during therapy, do not withhold the vaccine, and consider checking response or revaccinating when immunosuppression is reduced.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Belimumab و Human papillomavirus vaccine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Belimumab with Human papillomavirus vaccine?

MediHelp rates the interaction as moderate. Belimumab and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Belimumab suppresses B-cell survival and may blunt the antibody response to HPV vaccination. Protection may therefore be lower than expected, although the vaccine is non-live and not unsafe.

How serious is the interaction between Belimumab and Human papillomavirus vaccine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Where possible, complete HPV vaccination before starting belimumab. If given during therapy, do not withhold the vaccine, and consider checking response or revaccinating when immunosuppression is reduced.

What other medicines interact with Human papillomavirus vaccine?

MediHelp also lists interactions of Human papillomavirus vaccine with, for example, Antithymocyte globulin equine, Antithymocyte globulin rabbit, Atidarsagene autotemcel. The full list is on the Human papillomavirus vaccine page.

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