تداخل‌های دارویی
Benazepril + Bismuth subsalicylate
شدت: متوسط
Benazepril and Bismuth subsalicylate: moderate interaction.
آخرین به‌روزرسانی
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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Salicylate absorbed from bismuth subsalicylate can blunt the blood pressure lowering effect of ACE inhibitors and may add to renal risk, especially in volume depletion, such as during diarrhea. Acute kidney injury is a concern in dehydrated or older patients.
معنای این تداخل به زبان ساده
Benazepril and Bismuth subsalicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Benazepril belongs to Cardiovascular; Bismuth subsalicylate belongs to Gastrointestinal Tract.
چرا رخ می‌دهد
Salicylate-mediated inhibition of renal prostaglandins reduces vasodilation and renal perfusion, antagonizing ACE inhibitor effects.
اقدام لازم
Avoid regular or prolonged use of bismuth subsalicylate. In dehydrated patients monitor renal function, potassium and blood pressure.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Benazepril و Bismuth subsalicylate، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Bismuth subsalicylate
تداخلات دیگر Benazepril
پرسش‌های متداول
Can I take Benazepril with Bismuth subsalicylate?
MediHelp rates the interaction as moderate. Benazepril and Bismuth subsalicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Salicylate absorbed from bismuth subsalicylate can blunt the blood pressure lowering effect of ACE inhibitors and may add to renal risk, especially in volume depletion, such as during diarrhea. Acute kidney injury is a concern in dehydrated or older patients.
How serious is the interaction between Benazepril and Bismuth subsalicylate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid regular or prolonged use of bismuth subsalicylate. In dehydrated patients monitor renal function, potassium and blood pressure.
What other medicines interact with Bismuth subsalicylate?
MediHelp also lists interactions of Bismuth subsalicylate with, for example, Dichlorphenamide, Warfarin, Acetylsalicylic acid. The full list is on the Bismuth subsalicylate page.
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