تداخل‌های دارویی
Brentuximab + Etrasimod
شدت: شدید
Brentuximab and Etrasimod: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Brentuximab vedotin is cytotoxic and can cause neutropenia and serious infections, while etrasimod reduces circulating lymphocytes. Together they may add to infection risk, and etrasimod labeling advises against combining it with antineoplastic therapies. Effects of etrasimod persist for weeks after discontinuation.
معنای این تداخل به زبان ساده
Brentuximab and Etrasimod can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Brentuximab belongs to Oncology; Etrasimod belongs to Gastrointestinal Tract.
چرا رخ می‌دهد
Additive immunosuppression from myelosuppression due to the brentuximab vedotin payload and lymphocyte sequestration due to etrasimod.
اقدام لازم
Avoid combining where an alternative exists, including for weeks after stopping etrasimod. If unavoidable, monitor blood counts and watch for infection.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Brentuximab و Etrasimod، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Brentuximab
تداخلات دیگر Etrasimod
پرسش‌های متداول
Can I take Brentuximab with Etrasimod?
MediHelp rates the interaction as major. Brentuximab and Etrasimod can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Brentuximab vedotin is cytotoxic and can cause neutropenia and serious infections, while etrasimod reduces circulating lymphocytes. Together they may add to infection risk, and etrasimod labeling advises against combining it with antineoplastic therapies. Effects of etrasimod persist for weeks after discontinuation.
How serious is the interaction between Brentuximab and Etrasimod?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining where an alternative exists, including for weeks after stopping etrasimod. If unavoidable, monitor blood counts and watch for infection.
What other medicines interact with Brentuximab?
MediHelp also lists interactions of Brentuximab with, for example, Bleomycin, Dengue vaccine, Idelalisib. The full list is on the Brentuximab page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
