تداخل‌های دارویی
Capecitabine + Idecabtagene vicleucel
شدت: شدید
Capecitabine and Idecabtagene vicleucel: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Capecitabine causes myelosuppression and lymphopenia, which can add to the prolonged cytopenias and infection risk seen after CAR-T therapy. Chemotherapy given around the time of cell infusion may also impair CAR-T expansion and persistence.
معنای این تداخل به زبان ساده
Capecitabine and Idecabtagene vicleucel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Capecitabine belongs to Oncology; Idecabtagene vicleucel belongs to Oncology.
چرا رخ می‌دهد
Additive myelosuppressive and immunosuppressive effects, with possible cytotoxic effects on infused T cells.
اقدام لازم
Avoid capecitabine during lymphodepletion and the early period after CAR-T infusion unless clearly required. If used, monitor blood counts and infection signs closely and give anti-infective prophylaxis as per protocol.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Capecitabine و Idecabtagene vicleucel، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Capecitabine
تداخلات دیگر Idecabtagene vicleucel
پرسش‌های متداول
Can I take Capecitabine with Idecabtagene vicleucel?
MediHelp rates the interaction as major. Capecitabine and Idecabtagene vicleucel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Capecitabine causes myelosuppression and lymphopenia, which can add to the prolonged cytopenias and infection risk seen after CAR-T therapy. Chemotherapy given around the time of cell infusion may also impair CAR-T expansion and persistence.
How serious is the interaction between Capecitabine and Idecabtagene vicleucel?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid capecitabine during lymphodepletion and the early period after CAR-T infusion unless clearly required. If used, monitor blood counts and infection signs closely and give anti-infective prophylaxis as per protocol.
What other medicines interact with Capecitabine?
MediHelp also lists interactions of Capecitabine with, for example, Adenovirus types 4 and 7 live, Arsenic trioxide, Axicabtagene ciloleucel. The full list is on the Capecitabine page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
