تداخل‌های دارویی
Cefaclor + Kanamycin
شدت: متوسط
Cefaclor and Kanamycin: moderate interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Kanamycin is nephrotoxic and ototoxic, and cephalosporins have been reported occasionally to add to renal injury when given with aminoglycosides. Cefaclor is among the cephalosporins with a lower nephrotoxic potential, so the added risk is modest but relevant in patients with existing renal impairment.
معنای این تداخل به زبان ساده
Cefaclor and Kanamycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
چرا رخ می‌دهد
Additive nephrotoxicity, with possible reduction of aminoglycoside clearance when renal function worsens.
اقدام لازم
Monitor serum creatinine and urine output during combined therapy, and monitor aminoglycoside levels and hearing where applicable. Adjust doses to renal function.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Cefaclor و Kanamycin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Cefaclor
پرسش‌های متداول
Can I take Cefaclor with Kanamycin?
MediHelp rates the interaction as moderate. Cefaclor and Kanamycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Kanamycin is nephrotoxic and ototoxic, and cephalosporins have been reported occasionally to add to renal injury when given with aminoglycosides. Cefaclor is among the cephalosporins with a lower nephrotoxic potential, so the added risk is modest but relevant in patients with existing renal impairment.
How serious is the interaction between Cefaclor and Kanamycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and urine output during combined therapy, and monitor aminoglycoside levels and hearing where applicable. Adjust doses to renal function.
What other medicines interact with Cefaclor?
MediHelp also lists interactions of Cefaclor with, for example, Bcg vaccine live, Cholera vaccine, Microbiota. The full list is on the Cefaclor page.
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