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Cefaclor + Plazomicin

شدت: متوسط

Cefaclor and Plazomicin: moderate interaction.

آخرین به‌روزرسانی

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خلاصه

Plazomicin carries warnings for nephrotoxicity, ototoxicity and neuromuscular blockade. Cephalosporins have occasionally been associated with additive kidney injury when combined with aminoglycosides, although cefaclor has relatively low nephrotoxic potential.

معنای این تداخل به زبان ساده

Cefaclor and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Cefaclor belongs to Anti Bacterial; Plazomicin belongs to Anti Bacterial.

سطح شواهد: Low

چرا رخ می‌دهد

Additive nephrotoxic effects on the renal tubule.

اقدام لازم

Monitor serum creatinine and plazomicin concentrations during combined use, and adjust the plazomicin dose to renal function per labeling.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Cefaclor و Plazomicin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Cefaclor with Plazomicin?

MediHelp rates the interaction as moderate. Cefaclor and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Plazomicin carries warnings for nephrotoxicity, ototoxicity and neuromuscular blockade. Cephalosporins have occasionally been associated with additive kidney injury when combined with aminoglycosides, although cefaclor has relatively low nephrotoxic potential.

How serious is the interaction between Cefaclor and Plazomicin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and plazomicin concentrations during combined use, and adjust the plazomicin dose to renal function per labeling.

What other medicines interact with Cefaclor?

MediHelp also lists interactions of Cefaclor with, for example, Bcg vaccine live, Cholera vaccine, Kanamycin. The full list is on the Cefaclor page.

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