تداخل‌های دارویی
Cefadroxil + Kanamycin
شدت: متوسط
Cefadroxil and Kanamycin: moderate interaction.
آخرین به‌روزرسانی
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خلاصه
Aminoglycosides are nephrotoxic and ototoxic, and cephalosporins have occasionally been reported to add to renal injury when combined with them. Cefadroxil has little intrinsic nephrotoxicity, so the added risk is modest but matters in patients with reduced renal function. Both drugs are renally eliminated, so impairment raises exposure to each.
معنای این تداخل به زبان ساده
Cefadroxil and Kanamycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
چرا رخ می‌دهد
Additive renal tubular injury, with reduced renal clearance of both drugs when kidney function declines.
اقدام لازم
Monitor serum creatinine and aminoglycoside levels, and adjust doses to renal function. Ensure hydration and watch for hearing or balance changes.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Cefadroxil و Kanamycin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Cefadroxil
پرسش‌های متداول
Can I take Cefadroxil with Kanamycin?
MediHelp rates the interaction as moderate. Cefadroxil and Kanamycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aminoglycosides are nephrotoxic and ototoxic, and cephalosporins have occasionally been reported to add to renal injury when combined with them. Cefadroxil has little intrinsic nephrotoxicity, so the added risk is modest but matters in patients with reduced renal function. Both drugs are renally eliminated, so impairment raises exposure to each.
How serious is the interaction between Cefadroxil and Kanamycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and aminoglycoside levels, and adjust doses to renal function. Ensure hydration and watch for hearing or balance changes.
What other medicines interact with Cefadroxil?
MediHelp also lists interactions of Cefadroxil with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefadroxil page.
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