تداخلهای دارویی
Ceftazidime + Kanamycin
شدت: متوسط
Ceftazidime and Kanamycin: moderate interaction.
آخرین بهروزرسانی
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خلاصه
Ceftazidime given with an aminoglycoside such as kanamycin may add to kidney injury risk, and aminoglycosides also carry ototoxic potential. The risk is greatest in patients with pre-existing renal impairment, older age, dehydration or prolonged therapy. Combination is used clinically but warrants monitoring.
معنای این تداخل به زبان ساده
Ceftazidime and Kanamycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
چرا رخ میدهد
Additive nephrotoxicity, with aminoglycoside-related ototoxicity and renal accumulation possibly aggravated by reduced renal function.
اقدام لازم
Monitor serum creatinine and urine output regularly, and adjust ceftazidime and kanamycin doses to renal function. Check aminoglycoside levels where available and monitor hearing and vestibular symptoms.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیههای کامل مدیریت Ceftazidime و Kanamycin، یادداشتهای تکمیلی، جزئیات شواهد و بررسیکننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Ceftazidime
پرسشهای متداول
Can I take Ceftazidime with Kanamycin?
MediHelp rates the interaction as moderate. Ceftazidime and Kanamycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ceftazidime given with an aminoglycoside such as kanamycin may add to kidney injury risk, and aminoglycosides also carry ototoxic potential. The risk is greatest in patients with pre-existing renal impairment, older age, dehydration or prolonged therapy. Combination is used clinically but warrants monitoring.
How serious is the interaction between Ceftazidime and Kanamycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and urine output regularly, and adjust ceftazidime and kanamycin doses to renal function. Check aminoglycoside levels where available and monitor hearing and vestibular symptoms.
What other medicines interact with Ceftazidime?
MediHelp also lists interactions of Ceftazidime with, for example, Amikacin, Cholera vaccine, Dexamethasone-tobramycin. The full list is on the Ceftazidime page.
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