تداخل‌های دارویی
Cenobamate + Ethinyl estradiol-drospirenone
شدت: شدید
Cenobamate and Ethinyl estradiol-drospirenone: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Cenobamate induces CYP3A4 and can lower ethinyl estradiol exposure, which may reduce contraceptive effectiveness and increase the risk of breakthrough bleeding or unintended pregnancy. Drospirenone exposure may also be reduced.
معنای این تداخل به زبان ساده
Cenobamate and Ethinyl estradiol-drospirenone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cenobamate belongs to Central Nervous System; Ethinyl estradiol-drospirenone belongs to Endocrine.
چرا رخ می‌دهد
Cenobamate induces CYP3A4, increasing the metabolism of ethinyl estradiol and progestins.
اقدام لازم
Advise an additional or alternative non-hormonal contraceptive method while on cenobamate and for a period after stopping. Consider a non-hormonal method or an IUD as the primary option.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Cenobamate و Ethinyl estradiol-drospirenone، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Ethinyl estradiol-drospirenone
- Ethinyl estradiol-drospirenone + Fezolinetant منع مصرف
- Ethinyl estradiol-drospirenone + Ombitasvir / paritaprevir / ritonavir منع مصرف
- Ethinyl estradiol-drospirenone + Ombitasvir / paritaprevir / ritonavir and dasabuvir منع مصرف
- Ethinyl estradiol-drospirenone + Tranexamic acid منع مصرف
- Aminocaproic acid + Ethinyl estradiol-drospirenone شدید
- Amobarbital + Ethinyl estradiol-drospirenone شدید
تداخلات دیگر Cenobamate
پرسش‌های متداول
Can I take Cenobamate with Ethinyl estradiol-drospirenone?
MediHelp rates the interaction as major. Cenobamate and Ethinyl estradiol-drospirenone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cenobamate induces CYP3A4 and can lower ethinyl estradiol exposure, which may reduce contraceptive effectiveness and increase the risk of breakthrough bleeding or unintended pregnancy. Drospirenone exposure may also be reduced.
How serious is the interaction between Cenobamate and Ethinyl estradiol-drospirenone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise an additional or alternative non-hormonal contraceptive method while on cenobamate and for a period after stopping. Consider a non-hormonal method or an IUD as the primary option.
What other medicines interact with Ethinyl estradiol-drospirenone?
MediHelp also lists interactions of Ethinyl estradiol-drospirenone with, for example, Fezolinetant, Ombitasvir / paritaprevir / ritonavir, Ombitasvir / paritaprevir / ritonavir and dasabuvir. The full list is on the Ethinyl estradiol-drospirenone page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
