تداخلهای دارویی
Certolizumab pegol + Smallpox vaccine live
شدت: منع مصرف
Certolizumab pegol and Smallpox vaccine live: contraindicated interaction.
آخرین بهروزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصهای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمیشود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Smallpox (vaccinia) vaccine contains replicating live virus that can cause progressive vaccinia in immunosuppressed patients. Certolizumab increases this risk and may reduce vaccine effectiveness.
معنای این تداخل به زبان ساده
Certolizumab pegol and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
چرا رخ میدهد
TNF inhibition impairs cell-mediated control of replicating vaccinia virus.
اقدام لازم
Avoid vaccinia vaccine during certolizumab therapy unless risk of smallpox exposure clearly outweighs harm. Consider alternative non-replicating vaccines where available.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیههای کامل مدیریت Certolizumab pegol و Smallpox vaccine live، یادداشتهای تکمیلی، جزئیات شواهد و بررسیکننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Certolizumab pegol
- Adenovirus types 4 and 7 live + Certolizumab pegol منع مصرف
- Bcg intravesical live + Certolizumab pegol منع مصرف
- Bcg vaccine live + Certolizumab pegol منع مصرف
- Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal منع مصرف
- Certolizumab pegol + Measles mumps and rubella vaccine منع مصرف
- Certolizumab pegol + Measles mumps and rubella vaccine live منع مصرف
پرسشهای متداول
Can I take Certolizumab pegol with Smallpox vaccine live?
MediHelp rates the interaction as contraindicated. Certolizumab pegol and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Smallpox (vaccinia) vaccine contains replicating live virus that can cause progressive vaccinia in immunosuppressed patients. Certolizumab increases this risk and may reduce vaccine effectiveness.
How serious is the interaction between Certolizumab pegol and Smallpox vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid vaccinia vaccine during certolizumab therapy unless risk of smallpox exposure clearly outweighs harm. Consider alternative non-replicating vaccines where available.
What other medicines interact with Certolizumab pegol?
MediHelp also lists interactions of Certolizumab pegol with, for example, Adenovirus types 4 and 7 live, Bcg intravesical live, Bcg vaccine live. The full list is on the Certolizumab pegol page.
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