تداخل‌های دارویی
Colistin + Vancomycin
شدت: شدید
Colistin and Vancomycin: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Both vancomycin and colistin are nephrotoxic, and combination therapy has been associated with a higher incidence of acute kidney injury than either drug alone. Colistin also carries neurotoxicity risk.
معنای این تداخل به زبان ساده
Colistin and Vancomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Colistin belongs to Anti Bacterial; Vancomycin belongs to Anti Bacterial.
چرا رخ می‌دهد
Additive tubular nephrotoxicity from both drugs.
اقدام لازم
Monitor serum creatinine and urine output daily and use vancomycin level-guided dosing. Consider alternatives to vancomycin if gram-positive coverage is not essential.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Colistin و Vancomycin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Vancomycin
تداخلات دیگر Colistin
پرسش‌های متداول
Can I take Colistin with Vancomycin?
MediHelp rates the interaction as major. Colistin and Vancomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both vancomycin and colistin are nephrotoxic, and combination therapy has been associated with a higher incidence of acute kidney injury than either drug alone. Colistin also carries neurotoxicity risk.
How serious is the interaction between Colistin and Vancomycin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and urine output daily and use vancomycin level-guided dosing. Consider alternatives to vancomycin if gram-positive coverage is not essential.
What other medicines interact with Vancomycin?
MediHelp also lists interactions of Vancomycin with, for example, Amikacin, Bacitracin, Capreomycin. The full list is on the Vancomycin page.
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