تداخل‌های دارویی
Cyclobenzaprine + Selegiline transdermal
شدت: منع مصرف
Cyclobenzaprine and Selegiline transdermal: contraindicated interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Cyclobenzaprine is structurally related to tricyclic antidepressants, and its labeling contraindicates use with or within 14 days of MAO inhibitors. Combining it with selegiline, an MAO inhibitor, can cause serotonin syndrome, hypertensive crisis, severe convulsions, and death.
معنای این تداخل به زبان ساده
Cyclobenzaprine and Selegiline transdermal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
چرا رخ می‌دهد
Inhibition of MAO by selegiline combined with the serotonergic and noradrenergic reuptake effects of cyclobenzaprine leads to excess monoamine activity.
اقدام لازم
Avoid the combination and choose a non-serotonergic muscle relaxant. Allow a washout of at least 14 days after stopping an MAO inhibitor before starting cyclobenzaprine.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Cyclobenzaprine و Selegiline transdermal، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Cyclobenzaprine
- Cyclobenzaprine + Isocarboxazid منع مصرف
- Cyclobenzaprine + Linezolid منع مصرف
- Cyclobenzaprine + Phenelzine منع مصرف
- Cyclobenzaprine + Safinamide منع مصرف
- Cyclobenzaprine + Selegiline منع مصرف
- Cyclobenzaprine + Tranylcypromine منع مصرف
پرسش‌های متداول
Can I take Cyclobenzaprine with Selegiline transdermal?
MediHelp rates the interaction as contraindicated. Cyclobenzaprine and Selegiline transdermal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Cyclobenzaprine is structurally related to tricyclic antidepressants, and its labeling contraindicates use with or within 14 days of MAO inhibitors. Combining it with selegiline, an MAO inhibitor, can cause serotonin syndrome, hypertensive crisis, severe convulsions, and death.
How serious is the interaction between Cyclobenzaprine and Selegiline transdermal?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and choose a non-serotonergic muscle relaxant. Allow a washout of at least 14 days after stopping an MAO inhibitor before starting cyclobenzaprine.
What other medicines interact with Cyclobenzaprine?
MediHelp also lists interactions of Cyclobenzaprine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Cyclobenzaprine page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
