تداخل‌های دارویی
Cyclophosphamide + Deferiprone
شدت: شدید
Cyclophosphamide and Deferiprone: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Deferiprone can cause neutropenia and agranulocytosis, and cyclophosphamide is itself myelosuppressive. Combined use increases the risk of severe, potentially fatal infections.
معنای این تداخل به زبان ساده
Cyclophosphamide and Deferiprone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cyclophosphamide belongs to Oncology; Deferiprone belongs to Miscellaneous.
چرا رخ می‌دهد
Additive bone marrow suppression with pharmacodynamic synergy on neutrophil depletion.
اقدام لازم
Avoid the combination if possible. If necessary, monitor the absolute neutrophil count more frequently and interrupt deferiprone if neutropenia develops.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Cyclophosphamide و Deferiprone، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Cyclophosphamide
تداخلات دیگر Deferiprone
پرسش‌های متداول
Can I take Cyclophosphamide with Deferiprone?
MediHelp rates the interaction as major. Cyclophosphamide and Deferiprone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Deferiprone can cause neutropenia and agranulocytosis, and cyclophosphamide is itself myelosuppressive. Combined use increases the risk of severe, potentially fatal infections.
How serious is the interaction between Cyclophosphamide and Deferiprone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination if possible. If necessary, monitor the absolute neutrophil count more frequently and interrupt deferiprone if neutropenia develops.
What other medicines interact with Cyclophosphamide?
MediHelp also lists interactions of Cyclophosphamide with, for example, Adenovirus types 4 and 7 live, Belatacept, Bendamustine. The full list is on the Cyclophosphamide page.
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