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تداخل‌های دارویی

Cyclophosphamide + Dengue vaccine

شدت: شدید

Cyclophosphamide and Dengue vaccine: major interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Cyclophosphamide suppresses immune function and may blunt the antibody response to the dengue vaccine, leaving the patient inadequately protected. The dengue vaccine is live attenuated, so vaccination during significant immunosuppression also carries a risk of vaccine-related infection.

معنای این تداخل به زبان ساده

Cyclophosphamide and Dengue vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

سطح شواهد: Moderate

چرا رخ می‌دهد

Cytotoxic immunosuppression reduces vaccine immune response and impairs control of live attenuated virus replication.

اقدام لازم

Avoid giving the live dengue vaccine during cyclophosphamide therapy; vaccinate at least several weeks before starting treatment or after immune recovery, as advised by specialist guidance.

از داروساز چه بپرسید

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Cyclophosphamide و Dengue vaccine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Cyclophosphamide with Dengue vaccine?

MediHelp rates the interaction as major. Cyclophosphamide and Dengue vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cyclophosphamide suppresses immune function and may blunt the antibody response to the dengue vaccine, leaving the patient inadequately protected. The dengue vaccine is live attenuated, so vaccination during significant immunosuppression also carries a risk of vaccine-related infection.

How serious is the interaction between Cyclophosphamide and Dengue vaccine?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving the live dengue vaccine during cyclophosphamide therapy; vaccinate at least several weeks before starting treatment or after immune recovery, as advised by specialist guidance.

What other medicines interact with Cyclophosphamide?

MediHelp also lists interactions of Cyclophosphamide with, for example, Adenovirus types 4 and 7 live, Belatacept, Bendamustine. The full list is on the Cyclophosphamide page.

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