تداخل‌های دارویی
Dexamethasone-neomycin-polymyxin + Moxifloxacin
شدت: شدید
Dexamethasone-neomycin-polymyxin and Moxifloxacin: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Fluoroquinolones given with systemic corticosteroids increase the risk of tendinitis and tendon rupture. Older age and long treatment raise the risk further.
معنای این تداخل به زبان ساده
Dexamethasone-neomycin-polymyxin and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Dexamethasone-neomycin-polymyxin belongs to Anti Bacterial; Moxifloxacin belongs to Anti Bacterial.
چرا رخ می‌دهد
Additive tendon toxicity from fluoroquinolone effects on tenocytes and corticosteroid impairment of collagen synthesis.
اقدام لازم
Avoid the combination in older patients where an alternative antibiotic exists. Discontinue moxifloxacin at the first sign of tendon pain.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Dexamethasone-neomycin-polymyxin و Moxifloxacin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Dexamethasone-neomycin-polymyxin
- Dexamethasone-neomycin-polymyxin + Ketorolac شدید
- Dexamethasone-neomycin-polymyxin + Lapatinib شدید
- Dexamethasone-neomycin-polymyxin + Levofloxacin شدید
- Dexamethasone-neomycin-polymyxin + Mifepristone شدید
- Aldesleukin + Dexamethasone-neomycin-polymyxin متوسط
- Allogeneic cultured keratinocytes / fibroblasts in bovine collagen + Dexamethasone-neomycin-polymyxin متوسط
تداخلات دیگر Moxifloxacin
- Amiodarone + Moxifloxacin منع مصرف
- Arsenic trioxide + Moxifloxacin منع مصرف
- Disopyramide + Moxifloxacin منع مصرف
- Dofetilide + Moxifloxacin منع مصرف
- Dronedarone + Moxifloxacin منع مصرف
- Droperidol + Moxifloxacin منع مصرف
پرسش‌های متداول
Can I take Dexamethasone-neomycin-polymyxin with Moxifloxacin?
MediHelp rates the interaction as major. Dexamethasone-neomycin-polymyxin and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Fluoroquinolones given with systemic corticosteroids increase the risk of tendinitis and tendon rupture. Older age and long treatment raise the risk further.
How serious is the interaction between Dexamethasone-neomycin-polymyxin and Moxifloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination in older patients where an alternative antibiotic exists. Discontinue moxifloxacin at the first sign of tendon pain.
What other medicines interact with Dexamethasone-neomycin-polymyxin?
MediHelp also lists interactions of Dexamethasone-neomycin-polymyxin with, for example, Ketorolac, Lapatinib, Levofloxacin. The full list is on the Dexamethasone-neomycin-polymyxin page.
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