تداخل‌های دارویی
Dexamethasone-neomycin-polymyxin + Ketorolac
شدت: شدید
Dexamethasone-neomycin-polymyxin and Ketorolac: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Ketorolac carries a high intrinsic risk of GI ulceration and bleeding, and corticosteroids add to this risk. The combination is of concern with systemic exposure to dexamethasone.
معنای این تداخل به زبان ساده
Dexamethasone-neomycin-polymyxin and Ketorolac can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Dexamethasone-neomycin-polymyxin belongs to Anti Bacterial; Ketorolac belongs to Musculoskeletal.
چرا رخ می‌دهد
Additive gastrointestinal mucosal injury from corticosteroids and potent NSAID prostaglandin inhibition.
اقدام لازم
Keep ketorolac to the shortest course allowed by labeling and consider gastroprotection with a proton pump inhibitor. Avoid in patients with prior ulcer or GI bleed.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Dexamethasone-neomycin-polymyxin و Ketorolac، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Dexamethasone-neomycin-polymyxin
- Dexamethasone-neomycin-polymyxin + Lapatinib شدید
- Dexamethasone-neomycin-polymyxin + Levofloxacin شدید
- Dexamethasone-neomycin-polymyxin + Mifepristone شدید
- Dexamethasone-neomycin-polymyxin + Moxifloxacin شدید
- Aldesleukin + Dexamethasone-neomycin-polymyxin متوسط
- Allogeneic cultured keratinocytes / fibroblasts in bovine collagen + Dexamethasone-neomycin-polymyxin متوسط
تداخلات دیگر Ketorolac
- Aceclofenac + Ketorolac منع مصرف
- Acemetacin + Ketorolac منع مصرف
- Acetylsalicylic acid + Ketorolac منع مصرف
- Apixaban + Ketorolac منع مصرف
- Argatroban + Ketorolac منع مصرف
- Aspirin / citric acid / sodium bicarbonate + Ketorolac منع مصرف
پرسش‌های متداول
Can I take Dexamethasone-neomycin-polymyxin with Ketorolac?
MediHelp rates the interaction as major. Dexamethasone-neomycin-polymyxin and Ketorolac can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ketorolac carries a high intrinsic risk of GI ulceration and bleeding, and corticosteroids add to this risk. The combination is of concern with systemic exposure to dexamethasone.
How serious is the interaction between Dexamethasone-neomycin-polymyxin and Ketorolac?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Keep ketorolac to the shortest course allowed by labeling and consider gastroprotection with a proton pump inhibitor. Avoid in patients with prior ulcer or GI bleed.
What other medicines interact with Dexamethasone-neomycin-polymyxin?
MediHelp also lists interactions of Dexamethasone-neomycin-polymyxin with, for example, Lapatinib, Levofloxacin, Mifepristone. The full list is on the Dexamethasone-neomycin-polymyxin page.
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