تداخل‌های دارویی
Dextroamphetamine + Sodium bicarbonate
شدت: متوسط
Dextroamphetamine and Sodium bicarbonate: moderate interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Sodium bicarbonate alkalinizes the urine, which reduces the renal elimination of amphetamines. Dextroamphetamine exposure and duration of action can rise, increasing the risk of stimulant adverse effects such as tachycardia, hypertension, agitation and insomnia.
معنای این تداخل به زبان ساده
Dextroamphetamine and Sodium bicarbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dextroamphetamine belongs to Central Nervous System; Sodium bicarbonate belongs to Gastrointestinal Tract.
چرا رخ می‌دهد
Urinary alkalinization increases the non-ionized fraction of dextroamphetamine, enhancing tubular reabsorption and reducing renal clearance.
اقدام لازم
Monitor heart rate, blood pressure and signs of stimulant excess when systemic alkalinizing agents are used regularly. Consider reducing the dextroamphetamine dose if symptoms of overstimulation appear.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Dextroamphetamine و Sodium bicarbonate، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Dextroamphetamine
- Dextroamphetamine + Isocarboxazid منع مصرف
- Dextroamphetamine + Linezolid منع مصرف
- Dextroamphetamine + Methylene blue منع مصرف
- Dextroamphetamine + Phenelzine منع مصرف
- Dextroamphetamine + Rasagiline منع مصرف
- Dextroamphetamine + Safinamide منع مصرف
تداخلات دیگر Sodium bicarbonate
پرسش‌های متداول
Can I take Dextroamphetamine with Sodium bicarbonate?
MediHelp rates the interaction as moderate. Dextroamphetamine and Sodium bicarbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium bicarbonate alkalinizes the urine, which reduces the renal elimination of amphetamines. Dextroamphetamine exposure and duration of action can rise, increasing the risk of stimulant adverse effects such as tachycardia, hypertension, agitation and insomnia.
How serious is the interaction between Dextroamphetamine and Sodium bicarbonate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and signs of stimulant excess when systemic alkalinizing agents are used regularly. Consider reducing the dextroamphetamine dose if symptoms of overstimulation appear.
What other medicines interact with Dextroamphetamine?
MediHelp also lists interactions of Dextroamphetamine with, for example, Isocarboxazid, Linezolid, Methylene blue. The full list is on the Dextroamphetamine page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
