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Dihydroergotamine + Ergotamine

شدت: منع مصرف

Dihydroergotamine and Ergotamine: contraindicated interaction.

آخرین به‌روزرسانی

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خلاصه

Both are ergot alkaloids with vasoconstrictive actions. Together they can cause additive vasospasm and prolonged ischemia, and labeling advises against use of ergot drugs within a day of each other.

معنای این تداخل به زبان ساده

Dihydroergotamine and Ergotamine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Dihydroergotamine belongs to Central Nervous System; Ergotamine belongs to Central Nervous System.

سطح شواهد: High

چرا رخ می‌دهد

Additive vasoconstriction from ergot alkaloid agonism at serotonin and adrenergic receptors.

اقدام لازم

Do not use together or within 24 hours of each other. Choose a single ergot agent or a non-ergot alternative.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Dihydroergotamine و Ergotamine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Dihydroergotamine with Ergotamine?

MediHelp rates the interaction as contraindicated. Dihydroergotamine and Ergotamine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both are ergot alkaloids with vasoconstrictive actions. Together they can cause additive vasospasm and prolonged ischemia, and labeling advises against use of ergot drugs within a day of each other.

How serious is the interaction between Dihydroergotamine and Ergotamine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together or within 24 hours of each other. Choose a single ergot agent or a non-ergot alternative.

What other medicines interact with Ergotamine?

MediHelp also lists interactions of Ergotamine with, for example, Almotriptan, Atazanavir, Clarithromycin. The full list is on the Ergotamine page.

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