تداخل‌های دارویی
Dihydroergotamine intranasal + Phenylephrine
شدت: شدید
Dihydroergotamine intranasal and Phenylephrine: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Phenylephrine is an alpha-1 agonist vasoconstrictor and dihydroergotamine also constricts blood vessels, so combined use can produce marked vasoconstriction and a rise in blood pressure. Peripheral or cerebral ischemia is possible, especially with systemic phenylephrine exposure.
معنای این تداخل به زبان ساده
Dihydroergotamine intranasal and Phenylephrine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
چرا رخ می‌دهد
Additive pharmacodynamic vasoconstriction through alpha-adrenergic agonism and ergot-mediated serotonergic and adrenergic vascular effects.
اقدام لازم
Avoid systemic or repeated use of phenylephrine with dihydroergotamine; choose a non-vasoconstrictor alternative. If unavoidable, monitor blood pressure and watch for ischemic symptoms.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Dihydroergotamine intranasal و Phenylephrine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Phenylephrine
پرسش‌های متداول
Can I take Dihydroergotamine intranasal with Phenylephrine?
MediHelp rates the interaction as major. Dihydroergotamine intranasal and Phenylephrine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Phenylephrine is an alpha-1 agonist vasoconstrictor and dihydroergotamine also constricts blood vessels, so combined use can produce marked vasoconstriction and a rise in blood pressure. Peripheral or cerebral ischemia is possible, especially with systemic phenylephrine exposure.
How serious is the interaction between Dihydroergotamine intranasal and Phenylephrine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid systemic or repeated use of phenylephrine with dihydroergotamine; choose a non-vasoconstrictor alternative. If unavoidable, monitor blood pressure and watch for ischemic symptoms.
What other medicines interact with Phenylephrine?
MediHelp also lists interactions of Phenylephrine with, for example, Isocarboxazid, Phenelzine, Tranylcypromine. The full list is on the Phenylephrine page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
