تداخل‌های دارویی
Phenelzine + Phenylephrine
شدت: منع مصرف
Phenelzine and Phenylephrine: contraindicated interaction.
آخرین به‌روزرسانی
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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Phenelzine is an irreversible MAO inhibitor, which can greatly amplify the pressor response to sympathomimetics. A hypertensive crisis may occur.
معنای این تداخل به زبان ساده
Phenelzine and Phenylephrine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Phenelzine belongs to Central Nervous System; Phenylephrine belongs to Respiratory.
چرا رخ می‌دهد
Inhibition of MAO increases availability of norepinephrine and enhances the pressor response to phenylephrine.
اقدام لازم
Avoid systemic phenylephrine in patients taking MAO inhibitors, including for two weeks after stopping. Use a non-sympathomimetic decongestant alternative.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Phenelzine و Phenylephrine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Phenylephrine
تداخلات دیگر Phenelzine
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- Atomoxetine + Phenelzine منع مصرف
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- Brimonidine + Phenelzine منع مصرف
پرسش‌های متداول
Can I take Phenelzine with Phenylephrine?
MediHelp rates the interaction as contraindicated. Phenelzine and Phenylephrine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Phenelzine is an irreversible MAO inhibitor, which can greatly amplify the pressor response to sympathomimetics. A hypertensive crisis may occur.
How serious is the interaction between Phenelzine and Phenylephrine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid systemic phenylephrine in patients taking MAO inhibitors, including for two weeks after stopping. Use a non-sympathomimetic decongestant alternative.
What other medicines interact with Phenylephrine?
MediHelp also lists interactions of Phenylephrine with, for example, Isocarboxazid, Tranylcypromine, Bromocriptine. The full list is on the Phenylephrine page.
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