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تداخل‌های دارویی

Ephedrine + Rasagiline

شدت: منع مصرف

Ephedrine and Rasagiline: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Ephedrine releases norepinephrine and its pressor effect can be strongly potentiated by MAO inhibitors. This risks a hypertensive crisis.

معنای این تداخل به زبان ساده

Ephedrine and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Ephedrine belongs to Cardiovascular; Rasagiline belongs to Central Nervous System.

سطح شواهد: Moderate

چرا رخ می‌دهد

MAO inhibition increases neuronal norepinephrine stores and reduces metabolism, amplifying indirect sympathomimetic action of ephedrine.

اقدام لازم

Avoid ephedrine in patients on rasagiline. If a vasopressor is required in the perioperative setting, use a cautiously titrated direct-acting agent with close blood pressure monitoring.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Ephedrine و Rasagiline، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Ephedrine with Rasagiline?

MediHelp rates the interaction as contraindicated. Ephedrine and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ephedrine releases norepinephrine and its pressor effect can be strongly potentiated by MAO inhibitors. This risks a hypertensive crisis.

How serious is the interaction between Ephedrine and Rasagiline?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid ephedrine in patients on rasagiline. If a vasopressor is required in the perioperative setting, use a cautiously titrated direct-acting agent with close blood pressure monitoring.

What other medicines interact with Rasagiline?

MediHelp also lists interactions of Rasagiline with, for example, Atomoxetine, Brimonidine, Bupropion-naltrexone. The full list is on the Rasagiline page.

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