تداخل‌های دارویی
Fesoterodine + Thioridazine
شدت: شدید
Fesoterodine and Thioridazine: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Thioridazine has strong anticholinergic activity, so combined use markedly increases risk of dry mouth, constipation, urinary retention, confusion and tachycardia. Thioridazine is also a CYP2D6 substrate and inhibitor with a risk of QT prolongation.
معنای این تداخل به زبان ساده
Fesoterodine and Thioridazine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Fesoterodine belongs to Genitourinary; Thioridazine belongs to Central Nervous System.
چرا رخ می‌دهد
Additive antimuscarinic effects, with thioridazine's CYP2D6 inhibition potentially raising fesoterodine metabolite levels.
اقدام لازم
Avoid the combination where possible, particularly in elderly patients. If unavoidable, monitor for anticholinergic toxicity and ECG changes.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Fesoterodine و Thioridazine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Fesoterodine
تداخلات دیگر Thioridazine
- Abiraterone + Thioridazine منع مصرف
- Adagrasib + Thioridazine منع مصرف
- Amiodarone + Thioridazine منع مصرف
- Amisulpride + Thioridazine منع مصرف
- Amitriptyline + Thioridazine منع مصرف
- Amoxapine + Thioridazine منع مصرف
پرسش‌های متداول
Can I take Fesoterodine with Thioridazine?
MediHelp rates the interaction as major. Fesoterodine and Thioridazine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Thioridazine has strong anticholinergic activity, so combined use markedly increases risk of dry mouth, constipation, urinary retention, confusion and tachycardia. Thioridazine is also a CYP2D6 substrate and inhibitor with a risk of QT prolongation.
How serious is the interaction between Fesoterodine and Thioridazine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible, particularly in elderly patients. If unavoidable, monitor for anticholinergic toxicity and ECG changes.
What other medicines interact with Fesoterodine?
MediHelp also lists interactions of Fesoterodine with, for example, Bethanechol, Clozapine, Levoketoconazole. The full list is on the Fesoterodine page.
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