تداخل‌های دارویی
Flutamide + Pretomanid
شدت: شدید
Flutamide and Pretomanid: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Pretomanid-containing regimens are associated with hepatotoxicity, and flutamide also carries a boxed warning for liver injury. Combined use may increase the chance of serious liver damage.
معنای این تداخل به زبان ساده
Flutamide and Pretomanid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Flutamide belongs to Endocrine; Pretomanid belongs to Anti Bacterial.
چرا رخ می‌دهد
Additive hepatotoxicity.
اقدام لازم
Avoid flutamide during pretomanid therapy and use another antiandrogen if needed. If unavoidable, monitor liver enzymes frequently.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Flutamide و Pretomanid، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Flutamide
تداخلات دیگر Pretomanid
پرسش‌های متداول
Can I take Flutamide with Pretomanid?
MediHelp rates the interaction as major. Flutamide and Pretomanid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Pretomanid-containing regimens are associated with hepatotoxicity, and flutamide also carries a boxed warning for liver injury. Combined use may increase the chance of serious liver damage.
How serious is the interaction between Flutamide and Pretomanid?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid flutamide during pretomanid therapy and use another antiandrogen if needed. If unavoidable, monitor liver enzymes frequently.
What other medicines interact with Flutamide?
MediHelp also lists interactions of Flutamide with, for example, Idelalisib, Levoketoconazole, Pexidartinib. The full list is on the Flutamide page.
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