تداخل‌های دارویی
Flutamide + Valoctocogene roxaparvovec
شدت: شدید
Flutamide and Valoctocogene roxaparvovec: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Flutamide carries a boxed warning for hepatotoxicity, and valoctocogene roxaparvovec commonly causes transaminase elevations. Combining them may raise the risk of liver injury and complicate interpretation of liver tests.
معنای این تداخل به زبان ساده
Flutamide and Valoctocogene roxaparvovec can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Flutamide belongs to Endocrine; Valoctocogene roxaparvovec belongs to Miscellaneous.
چرا رخ می‌دهد
Additive hepatotoxicity from two agents that each can injure the liver.
اقدام لازم
Avoid flutamide where possible around gene therapy; if unavoidable, monitor ALT/AST frequently and use an alternative antiandrogen with less hepatotoxic potential.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Flutamide و Valoctocogene roxaparvovec، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Flutamide
تداخلات دیگر Valoctocogene roxaparvovec
پرسش‌های متداول
Can I take Flutamide with Valoctocogene roxaparvovec?
MediHelp rates the interaction as major. Flutamide and Valoctocogene roxaparvovec can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Flutamide carries a boxed warning for hepatotoxicity, and valoctocogene roxaparvovec commonly causes transaminase elevations. Combining them may raise the risk of liver injury and complicate interpretation of liver tests.
How serious is the interaction between Flutamide and Valoctocogene roxaparvovec?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid flutamide where possible around gene therapy; if unavoidable, monitor ALT/AST frequently and use an alternative antiandrogen with less hepatotoxic potential.
What other medicines interact with Flutamide?
MediHelp also lists interactions of Flutamide with, for example, Idelalisib, Levoketoconazole, Pexidartinib. The full list is on the Flutamide page.
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