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تداخل‌های دارویی

Ganciclovir + Talimogene laherparepvec

شدت: شدید

Ganciclovir and Talimogene laherparepvec: major interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Talimogene laherparepvec is a live, attenuated herpes simplex virus that must replicate in tumor cells. Ganciclovir is active against herpes viruses and may suppress this replication, reducing the efficacy of the oncolytic therapy.

معنای این تداخل به زبان ساده

Ganciclovir and Talimogene laherparepvec can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Ganciclovir belongs to Anti Virals; Talimogene laherparepvec belongs to Oncology.

سطح شواهد: Low

چرا رخ می‌دهد

Antiviral inhibition of viral DNA replication, which may blunt the activity of the live oncolytic virus.

اقدام لازم

Avoid antiherpetic antivirals during talimogene therapy where possible. If ganciclovir is needed for a herpes infection, such as an infection attributed to the vector, treat it and reassess the oncolytic regimen.

از داروساز چه بپرسید

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Ganciclovir و Talimogene laherparepvec، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۷ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Ganciclovir with Talimogene laherparepvec?

MediHelp rates the interaction as major. Ganciclovir and Talimogene laherparepvec can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Talimogene laherparepvec is a live, attenuated herpes simplex virus that must replicate in tumor cells. Ganciclovir is active against herpes viruses and may suppress this replication, reducing the efficacy of the oncolytic therapy.

How serious is the interaction between Ganciclovir and Talimogene laherparepvec?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid antiherpetic antivirals during talimogene therapy where possible. If ganciclovir is needed for a herpes infection, such as an infection attributed to the vector, treat it and reassess the oncolytic regimen.

What other medicines interact with Ganciclovir?

MediHelp also lists interactions of Ganciclovir with, for example, Bacitracin, Cilastatin-imipenem, Didanosine. The full list is on the Ganciclovir page.

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