تداخل‌های دارویی
Hydroxyurea + Interferon beta 1a
شدت: شدید
Hydroxyurea and Interferon beta 1a: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Cutaneous vasculitic toxicities, including ulceration and gangrene, have been reported in patients receiving hydroxyurea who have current or prior interferon exposure. The events can be severe and may require stopping therapy.
معنای این تداخل به زبان ساده
Hydroxyurea and Interferon beta 1a can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Hydroxyurea belongs to Miscellaneous; Interferon beta 1a belongs to Central Nervous System.
چرا رخ می‌دهد
The mechanism is not well established; additive vascular and cutaneous toxicity is suspected.
اقدام لازم
Examine the skin regularly for ulceration or vasculitic lesions and discontinue hydroxyurea if they develop; consider alternatives in patients with prior interferon exposure.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Hydroxyurea و Interferon beta 1a، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Interferon beta 1a
تداخلات دیگر Hydroxyurea
پرسش‌های متداول
Can I take Hydroxyurea with Interferon beta 1a?
MediHelp rates the interaction as major. Hydroxyurea and Interferon beta 1a can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cutaneous vasculitic toxicities, including ulceration and gangrene, have been reported in patients receiving hydroxyurea who have current or prior interferon exposure. The events can be severe and may require stopping therapy.
How serious is the interaction between Hydroxyurea and Interferon beta 1a?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Examine the skin regularly for ulceration or vasculitic lesions and discontinue hydroxyurea if they develop; consider alternatives in patients with prior interferon exposure.
What other medicines interact with Interferon beta 1a?
MediHelp also lists interactions of Interferon beta 1a with, for example, Deferiprone, Etrasimod, Idecabtagene vicleucel. The full list is on the Interferon beta 1a page.
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