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تداخل‌های دارویی

Ifosfamide + Measles mumps and rubella vaccine

شدت: منع مصرف

Ifosfamide and Measles mumps and rubella vaccine: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Ifosfamide is a cytotoxic alkylating agent that depletes lymphocytes and neutrophils, so live attenuated measles, mumps, rubella and varicella vaccine viruses may replicate without control. This can lead to disseminated vaccine-strain disease and the vaccine also gives poor protection.

معنای این تداخل به زبان ساده

Ifosfamide and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Ifosfamide belongs to Oncology; Measles mumps and rubella vaccine belongs to Miscellaneous.

سطح شواهد: High

چرا رخ می‌دهد

Immunosuppression permits replication of live attenuated vaccine viruses: myelosuppression and lymphocyte depletion

اقدام لازم

Do not give live vaccines during chemotherapy; vaccinate at least 4 weeks before starting and defer until immune recovery (usually at least 3 months after treatment ends).

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Ifosfamide و Measles mumps and rubella vaccine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Ifosfamide with Measles mumps and rubella vaccine?

MediHelp rates the interaction as contraindicated. Ifosfamide and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ifosfamide is a cytotoxic alkylating agent that depletes lymphocytes and neutrophils, so live attenuated measles, mumps, rubella and varicella vaccine viruses may replicate without control. This can lead to disseminated vaccine-strain disease and the vaccine also gives poor protection.

How serious is the interaction between Ifosfamide and Measles mumps and rubella vaccine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines during chemotherapy; vaccinate at least 4 weeks before starting and defer until immune recovery (usually at least 3 months after treatment ends).

What other medicines interact with Measles mumps and rubella vaccine?

MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.

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