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تداخل‌های دارویی

Azathioprine + Measles mumps and rubella vaccine

شدت: منع مصرف

Azathioprine and Measles mumps and rubella vaccine: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

The live attenuated vaccine relies on a competent immune system to limit viral replication, and azathioprine (a purine-antimetabolite immunosuppressant) weakens that control. Disseminated vaccine-strain infection is possible and the antibody response to the vaccine may also be reduced.

معنای این تداخل به زبان ساده

Azathioprine and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Azathioprine belongs to Gastrointestinal Tract; Measles mumps and rubella vaccine belongs to Miscellaneous.

سطح شواهد: High

چرا رخ می‌دهد

Azathioprine-mediated immunosuppression allows replication of a live attenuated virus

اقدام لازم

Do not give live vaccines during treatment; where possible, vaccinate at least 4 weeks before starting the immunosuppressant, and delay after stopping until immune function has recovered.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Azathioprine و Measles mumps and rubella vaccine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Azathioprine with Measles mumps and rubella vaccine?

MediHelp rates the interaction as contraindicated. Azathioprine and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The live attenuated vaccine relies on a competent immune system to limit viral replication, and azathioprine (a purine-antimetabolite immunosuppressant) weakens that control. Disseminated vaccine-strain infection is possible and the antibody response to the vaccine may also be reduced.

How serious is the interaction between Azathioprine and Measles mumps and rubella vaccine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines during treatment; where possible, vaccinate at least 4 weeks before starting the immunosuppressant, and delay after stopping until immune function has recovered.

What other medicines interact with Measles mumps and rubella vaccine?

MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.

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