تداخل‌های دارویی
Insulin degludec / insulin aspart + Megestrol
شدت: متوسط
Insulin degludec / insulin aspart and Megestrol: moderate interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Megestrol has glucocorticoid-like activity and can raise blood glucose and worsen insulin resistance. Patients on insulin may therefore need higher doses to maintain glycemic control. Hyperglycemia may emerge or worsen during therapy.
معنای این تداخل به زبان ساده
Insulin degludec / insulin aspart and Megestrol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
چرا رخ می‌دهد
Pharmacodynamic antagonism through glucocorticoid-like effects of megestrol causing insulin resistance and reduced glucose tolerance.
اقدام لازم
Monitor blood glucose more frequently when megestrol is started, changed or stopped. Titrate insulin doses, and reduce them again after megestrol is withdrawn.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Insulin degludec / insulin aspart و Megestrol، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Megestrol
پرسش‌های متداول
Can I take Insulin degludec / insulin aspart with Megestrol?
MediHelp rates the interaction as moderate. Insulin degludec / insulin aspart and Megestrol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Megestrol has glucocorticoid-like activity and can raise blood glucose and worsen insulin resistance. Patients on insulin may therefore need higher doses to maintain glycemic control. Hyperglycemia may emerge or worsen during therapy.
How serious is the interaction between Insulin degludec / insulin aspart and Megestrol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more frequently when megestrol is started, changed or stopped. Titrate insulin doses, and reduce them again after megestrol is withdrawn.
What other medicines interact with Megestrol?
MediHelp also lists interactions of Megestrol with, for example, Dofetilide, Insulin degludec-insulin aspart, Insulin degludec-liraglutide. The full list is on the Megestrol page.
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