تداخلهای دارویی
Insulin degludec-insulin aspart + Megestrol
شدت: متوسط
Insulin degludec-insulin aspart and Megestrol: moderate interaction.
آخرین بهروزرسانی
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خلاصه
Megestrol has glucocorticoid-like activity and can cause hyperglycemia, worsening diabetes control and increasing insulin requirements. Effects are more evident at the higher doses used for appetite stimulation.
معنای این تداخل به زبان ساده
Insulin degludec-insulin aspart and Megestrol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Insulin degludec-insulin aspart belongs to Endocrine; Megestrol belongs to Oncology.
چرا رخ میدهد
Progestogen with glucocorticoid activity that induces insulin resistance, opposing insulin action.
اقدام لازم
Monitor blood glucose regularly during megestrol therapy and increase the insulin dose as needed. Reduce the insulin dose again when megestrol is stopped.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیههای کامل مدیریت Insulin degludec-insulin aspart و Megestrol، یادداشتهای تکمیلی، جزئیات شواهد و بررسیکننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Insulin degludec-insulin aspart
تداخلات دیگر Megestrol
پرسشهای متداول
Can I take Insulin degludec-insulin aspart with Megestrol?
MediHelp rates the interaction as moderate. Insulin degludec-insulin aspart and Megestrol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Megestrol has glucocorticoid-like activity and can cause hyperglycemia, worsening diabetes control and increasing insulin requirements. Effects are more evident at the higher doses used for appetite stimulation.
How serious is the interaction between Insulin degludec-insulin aspart and Megestrol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose regularly during megestrol therapy and increase the insulin dose as needed. Reduce the insulin dose again when megestrol is stopped.
What other medicines interact with Insulin degludec-insulin aspart?
MediHelp also lists interactions of Insulin degludec-insulin aspart with, for example, Chlorpropamide, Clozapine, Diazoxide. The full list is on the Insulin degludec-insulin aspart page.
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