تداخل‌های دارویی
Insulin detemir + Pioglitazone
شدت: شدید
Insulin detemir and Pioglitazone: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Pioglitazone with insulin increases the risk of fluid retention, edema and heart failure and adds to glucose lowering with a risk of hypoglycemia.
معنای این تداخل به زبان ساده
Insulin detemir and Pioglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin detemir belongs to Endocrine; Pioglitazone belongs to Endocrine.
چرا رخ می‌دهد
Thiazolidinedione-induced sodium and fluid retention is additive with insulin's antinatriuretic effect, and both lower glucose through additive pharmacodynamic action.
اقدام لازم
Monitor for weight gain, edema and heart failure symptoms, and avoid in patients with significant cardiac disease. Reduce the insulin dose if hypoglycemia occurs.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Insulin detemir و Pioglitazone، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Insulin detemir
تداخلات دیگر Pioglitazone
پرسش‌های متداول
Can I take Insulin detemir with Pioglitazone?
MediHelp rates the interaction as major. Insulin detemir and Pioglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Pioglitazone with insulin increases the risk of fluid retention, edema and heart failure and adds to glucose lowering with a risk of hypoglycemia.
How serious is the interaction between Insulin detemir and Pioglitazone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for weight gain, edema and heart failure symptoms, and avoid in patients with significant cardiac disease. Reduce the insulin dose if hypoglycemia occurs.
What other medicines interact with Insulin detemir?
MediHelp also lists interactions of Insulin detemir with, for example, Alogliptin-pioglitazone, Ethanol, Glimepiride-pioglitazone. The full list is on the Insulin detemir page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
