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تداخل‌های دارویی

Ixekizumab + Lomustine

شدت: متوسط

Ixekizumab and Lomustine: moderate interaction.

آخرین به‌روزرسانی

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خلاصه

Lomustine causes myelosuppression and immune suppression, while ixekizumab blocks IL-17A signaling and impairs host defense. Together they may raise the risk of serious bacterial, fungal or opportunistic infections.

معنای این تداخل به زبان ساده

Ixekizumab and Lomustine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Ixekizumab belongs to Miscellaneous; Lomustine belongs to Oncology.

سطح شواهد: Low

چرا رخ می‌دهد

Additive immunosuppression: cytotoxic marrow suppression plus IL-17A antagonism.

اقدام لازم

Screen for active infection before and during therapy and monitor neutrophil counts. Hold ixekizumab if a serious infection develops.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Ixekizumab و Lomustine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Ixekizumab with Lomustine?

MediHelp rates the interaction as moderate. Ixekizumab and Lomustine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lomustine causes myelosuppression and immune suppression, while ixekizumab blocks IL-17A signaling and impairs host defense. Together they may raise the risk of serious bacterial, fungal or opportunistic infections.

How serious is the interaction between Ixekizumab and Lomustine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Screen for active infection before and during therapy and monitor neutrophil counts. Hold ixekizumab if a serious infection develops.

What other medicines interact with Lomustine?

MediHelp also lists interactions of Lomustine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Lomustine page.

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