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Lithium + Sodium polystyrene sulfonate

شدت: متوسط

Lithium and Sodium polystyrene sulfonate: moderate interaction.

آخرین به‌روزرسانی

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خلاصه

Sodium polystyrene sulfonate is a cation-exchange resin that can bind lithium in the gut and lower its absorption and serum concentration. It is also used to treat lithium overdose, so unintended lithium loss could reduce mood-stabilising effect.

معنای این تداخل به زبان ساده

Lithium and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Lithium belongs to Central Nervous System; Sodium polystyrene sulfonate belongs to Miscellaneous.

سطح شواهد: Moderate

چرا رخ می‌دهد

Cation-exchange resin binds lithium in the gastrointestinal tract, reducing absorption.

اقدام لازم

Separate doses by at least several hours, giving lithium well before the resin, and monitor serum lithium during prolonged co-therapy.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Lithium و Sodium polystyrene sulfonate، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Lithium with Sodium polystyrene sulfonate?

MediHelp rates the interaction as moderate. Lithium and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium polystyrene sulfonate is a cation-exchange resin that can bind lithium in the gut and lower its absorption and serum concentration. It is also used to treat lithium overdose, so unintended lithium loss could reduce mood-stabilising effect.

How serious is the interaction between Lithium and Sodium polystyrene sulfonate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses by at least several hours, giving lithium well before the resin, and monitor serum lithium during prolonged co-therapy.

What other medicines interact with Lithium?

MediHelp also lists interactions of Lithium with, for example, Thioridazine, Vandetanib, Aceclofenac. The full list is on the Lithium page.

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