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Magnesium hydroxide + Sodium polystyrene sulfonate

شدت: متوسط

Magnesium hydroxide and Sodium polystyrene sulfonate: moderate interaction.

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خلاصه

Magnesium hydroxide taken with sodium polystyrene sulfonate can lead to metabolic alkalosis because the resin binds the magnesium, leaving bicarbonate unneutralized. Rarely, intestinal obstruction from non-absorbable antacid and resin has been described.

معنای این تداخل به زبان ساده

Magnesium hydroxide and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Magnesium hydroxide belongs to Gastrointestinal Tract; Sodium polystyrene sulfonate belongs to Miscellaneous.

سطح شواهد: Moderate

چرا رخ می‌دهد

The resin binds magnesium in the gut, preventing neutralization of bicarbonate and leading to systemic alkalosis.

اقدام لازم

Avoid giving magnesium-containing antacids or laxatives with the resin, and separate doses by at least 2 hours if both are needed. Monitor acid-base status and electrolytes.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Magnesium hydroxide و Sodium polystyrene sulfonate، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Magnesium hydroxide with Sodium polystyrene sulfonate?

MediHelp rates the interaction as moderate. Magnesium hydroxide and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Magnesium hydroxide taken with sodium polystyrene sulfonate can lead to metabolic alkalosis because the resin binds the magnesium, leaving bicarbonate unneutralized. Rarely, intestinal obstruction from non-absorbable antacid and resin has been described.

How serious is the interaction between Magnesium hydroxide and Sodium polystyrene sulfonate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving magnesium-containing antacids or laxatives with the resin, and separate doses by at least 2 hours if both are needed. Monitor acid-base status and electrolytes.

What other medicines interact with Magnesium hydroxide?

MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.

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